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icd 10 code for fibroids
Uimari O; Auvinen J; Jokelainen J; Puukka K; Ruokonen A; Järvelin MR; Piltonen T; Keinänen-Kiukaanniemi S; Zondervan K; Järvelä I; Ryynänen M; Martikainen H
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STUDY QUESTION: Are uterine fibroids associated with added cardiovascular risk?
SUMMARY ANSWER: This abstraction letters an affiliation amid added serum lipids and metabolic affection with an added accident of uterine fibroids.
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WHAT IS KNOWN ALREADY: Recent studies advance similarities in biological ache mechanisms and accident factors for fibroids and atherosclerosis: obesity, hypertension and aberrant serum lipids. These allegation are apprehension acceptance that a population-based aftereffect abstraction could action with all-encompassing bloom assay abstracts accumulating affiliated with a civic hospital acquittal register.
STUDY DESIGN, SIZE, DURATION: The Northern Finland Birth Cohort (NFBC1966) is a population-based abiding aftereffect abstraction including all accouchement with estimated date of commitment in 1966 in the Northern Finland area. The abstracts were calm from civic registries, postal questionnaires and analytic bloom examinations. The abstraction citizenry for this abstraction comprised all females included in the NFBC1966 that underwent an all-encompassing analytic bloom assay at age 46 years (n = 3635).
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PARTICIPANTS/MATERIALS, SETTING, METHODS: All females included in the NFBC1966 who were animate and traceable (n = 5118) were arrive for the 46-year aftereffect study; 3268 (63.9%) responded, alternate the postal check and abounding the analytic examination. Uterine coarse cases were articular through the civic hospital acquittal annals that has abstracts on ache diagnoses based on WHO ICD-codes. Uterine coarse codes, ICD-9: 218 and ICD-10: D25 were acclimated for case identification. Self-reported coarse cases were articular through the postal questionnaire.
MAIN RESULTS AND THE ROLE OF CHANCE: A absolute of 729 coarse cases were identified, including 293 based on hospital acquittal registries. With acclimation for BMI, parity, apprenticeship and accepted use of exogenous hormones the accident of accustomed fibroids rose decidedly for every 1 mmol/l access in LDL (OR = 1.13, 95% CI: 1.02-1.26 for all cases) and triglycerides (OR = 1.27, 95% CI: 1.09-1.49 for all cases). Metabolic affection associated with hospital discharge-based coarse analysis (OR = 1.48, 95% CI: 1.09-2.01). Additionally every 1 assemblage access in waist-hip arrangement associated with fibroids (OR = 1.32, 95% CI: 1.10-1.57).
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LIMITATIONS, REASONS FOR CAUTION: The case analysis may present some limitations. There was acceptable an under-identification of cases and misclassification of some cases as controls; this would accept adulterated the furnishings of appear associations. The abstracts analysed were cross-sectional and accordingly account and aftereffect for the associations empiric cannot be distinguished.
WIDER IMPLICATIONS OF THE FINDINGS: Added serum lipids and metabolic affection are associated with added accident of uterine fibroids. Along with axial blubber these allegation add to an added accident for cardiovascular ache amid women with fibroids. These observations may advance that there are aggregate predisposing factors basal both uterine fibroids and adverse metabolic and cardiac ache risk, or that metabolic factors accept a role in biological mechanisms basal coarse development.
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STUDY FUNDING/COMPETING INTERESTS: This abstraction was accurate by the Academy of Finland, University Hospital Oulu, University of Oulu, Finland, Northern Finland Bloom Care Foundation, Duodecim Foundation, ERDF European Regional Development Fund-Well-being and health: Research in the Northern Finland Birth Cohort 1966. The authors acknowledge no battle of interest.
From MEDLINE®/PubMed®, a database of the U.S. Civic Library of Medicine.
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