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July 29, 2009 (Bonn, Germany) — Patients with a non–pacemaker-dependent implantable cardioverter defibrillator (ICD) can cautiously abide an MRI browse provided assertive precautions are taken, according to the after-effects of a new abstraction [1].
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Utilizing the assorted ICD, MRI, and monitoring-related assurance precautions, board did not beam any accident to the ICD systems or any abrupt changes in affection amount or rhythm. Also, there were no inappropriate shocks delivered and no affirmation of radiofrequency-related myocardial thermal accident during or afterwards the scan.
"The cardinal of built-in pacemakers and ICDs, as able-bodied as the cardinal of accessories for cardiac resynchronization therapy, are activity up every year," said advance investigator Dr Claas Philip Naehle (University of Bonn, Germany). "People are accepting older, and the earlier they get, the greater the likelihood they're activity to charge an MRI exam. Obviously that's a big overlap, and it's why we're seeing a lot of patients referred to us for an MRI exam."
The after-effects of the abstraction are appear in the August 4, 2009 affair of the Journal of the American College of Cardiology.
Assess if the Accommodating Needs the Exam
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Speaking with heartwire , Naehle said MRI scans in patients with an ICD are still an off-label procedure, but there are circumstances, such as a academician scan, area the modality's unparalleled adeptness to discriminate amid bendable tissue is advised medically necessary.
One of the primary apropos back a accommodating with an ICD undergoes an MRI browse is the careless heating of the built-in leads, which can account tissue accident and changes in thresholds. Added apropos accommodate movement of the accessory and abeyant accident of capture. With added pacemaker devices, there are apropos about programming changes, asynchronous pacing, activation of tachyarrhythmia therapies, inhibition of pacing output, and induced advance currents that could advance to cardiac stimulation.
"The aboriginal affair you charge to appraise is if the accommodating really, absolutely needs the exam," said Naehle. "The account of the MRI assay has to outweigh the risk. For instance, if you doubtable a academician tumor, there absolutely isn't abundant choice. You charge to do the MRI for a able diagnosis. If you artlessly appetite to see if there is a analgesic problem, say a alight of the discus in the spine, that ability be article that could be done by [computed tomography] CT."
In this study, 18 non–pacemaker-dependent ICD patients with a analytic charge for MRI, including bristles who appropriate scans of the heart, underwent an examination. Above-mentioned to the scan, the ICDs were reprogrammed to abstain aggressive pacing and abeyant arrhythmias. In anniversary patient, the lower amount absolute was programmed as low as possible, and arrhythmia apprehension remained on, but analysis commitment was programmed off. In accession to these precautions, the specific assimilation rate, a admeasurement of the activity captivated by the anatomy back apparent to a radiofrequency electromagnetic field, was bound to 2W/kg.
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After the MRI scan, an claiming of the ICD appear no cogent changes of pacing abduction beginning or advance impedance. Also, serum troponin I levels, a admeasurement of clinically accordant thermal injury, were banausic from baseline. No accommodating appear any torque or heating sensations or added abnormal affection during the MRI.
Despite the acknowledged scans, Naehle told heartwire that "only centers that apperceive what they're accomplishing should be accomplishing it." He said physicians should consistently actuate whether the ICD accommodating has undergone a above-mentioned MR browse because the accessory ability be damaged, and how many, if any, ventricular arrhythmias acute defibrillation occurred in the accomplished ages or so. He added that to be performed safely, there is a charge for accord amid the cardiologist/electrophysiologist and the radiologist. With earlier patients accepting added and added accessories implanted, accomplished centers are acceptable to be added active with referrals for these circuitous patients, he added.
No Absolute Account on MR and ICDs and Pacemakers
In 2007, the American Affection Association issued a account on the use of MRI in patients with cardiovascular diseases and included advice on application the scans in patients with ICDs and pacemakers. While there are currently no MRI-safe ICDs, the accurate address does not accommodate any absolute statements on their use and instead recommends that an MRI be performed alone in ICD and pacemaker patients who charge them and alone at able MRI and electrophysiology centers.
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In an beat accompanying the appear abstraction [2], Dr Ariel Roguin (Technion–Israel Institute of Technology, Haifa, Israel) addendum that ICDs accept added circuitous technology than pacemakers and accept beyond capacitors and batteries. As a result, the alluring armament are greater, and they are apparently added decumbent to electromagnetic and automated arrest back a accommodating with an ICD undergoes MRI. However, as Naehle told heartwire , ICD patients tend to be higher-risk patients, with college bloodshed rates, so the beginning of account for an MR browse charge additionally be higher.
Roguin credibility out that although abstracts are limited, it is estimated that at atomic 50% of patients with an built-in accessory will apparently charge to abide MRI over the lifetime of their device. Early abstracts on the about assurance of MR scans in device-implanted patients showed that no deaths accept occurred in assorted physician-supervised MR studies area patients are anxiously monitored, but there accept been a few cases of changes in pacing threshold, the charge for accessory reprogramming, and possibly array depletion.
"We charge exercise caution, however, accustomed the advanced ambit of accessible MRI systems, MRI scanning conditions, accommodating positions, pacemaker and ICD systems, and leads back extending these after-effects to recommendations for accepted use of MRI in these patients," writes Roguin. "The actuality that several hundreds of patients with [implanted devices] underwent boring MRI does not acquiesce us to achieve that MRI in this citizenry is absolutely safe. All appear studies were performed at centers with ability in MRI and electrophysiology and were bound to patients with a accurate analytic charge for MRI."
Like Naehle, Roguin stresses that MRI may be advised in called patients and done alone back clinically indicated.
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Roguin is a adviser to Medtronic. Naehle letters no conflicts of interest.
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