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All abstracts are acquired from individual-level registers at Statistics Denmark. For anniversary of the years 1981–2006, advice on labour bazaar amalgamation for anniversary actuality active in Denmark and age-old 16 years or earlier was acquired from Integrated Database for Labour Bazaar Research (IDA),[25] and application the altered Danish claimed identification number,[26] anniversary actuality was followed over the period. Furthermore, anniversary actuality was in 1996–2006 followed in the Danish Patient Register[27] in adjustment to ascertain aboriginal surgically advised hip and knee OA and in the Danish Civil Registration Arrangement to see if she dies or emigrates.
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Persons in our abstraction are from one of the afterward bristles anatomic groups absolute both accomplished and unskilled workers:
Floor layers/bricklayers/pavers (hereafter referred to as floor- and bricklayers): assignment with attic and bank covering, bricklaying and paving.
Construction workers: absolute architecture assignment such as architecture of buildings, insulation, carpentry, painting, accouterments and electrical work. This accumulation additionally includes floor- and bricklayers.
Farmers: agronomical and agronomical work.
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Healthcare assistants: nursing assistants, nursing aides and agnate bloom caretakers in the healthcare and amusing system.
Office workers: accounting staff, accounting agents and computer agents aural banks, costs and insurance.
Persons in accumulation 1–4 were advised to be exposed, while accumulation 5 serves as control. We accept that controls were commensurable with our abstraction groups with attention to socioeconomic cachet and not apparent to jobs with aerial concrete load.
We acclimated several sources to ascertain the activity groups in adjustment to ensure acceptable coverage.[28] A actuality was in a specific accumulation if he or she either (a) had adapted assignment skills/position or (b) formed at an adapted establishment[25] and had an adapted abstruse aggressive education.
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IDA in itself contains advice from several registers.[25] From 1981 to 1991, assignment skills/position was coded according to a allocation based on the assignment position and from 1992 according to abilities adapted to accomplish assignment functions application the Danish adaptation of the International Accepted Allocation of Occupations (ISCO 88). Both classifications are based on advice from the Danish tax arrangement application the assets register.[29]
IDA provides the achievability to articulation advice on enactment to individual-level advice for anniversary actuality anniversary year.[25] Advice on the industry of anniversary enactment is coded according to the Danish adaptation of the European Industrial Allocation of all Economic Activities (NACE). Only advice on the enactment area the actuality was active abounding time was used.
Information on accomplished accomplished akin of vocationally aggressive education[30] is coded with an eight-digit apprenticeship code. The aboriginal two digits accommodate advice on the akin of apprenticeship (eg, aerial school, vocational, bachelor), the afterward two digits announce the blazon of apprenticeship (eg, architecture construction), digits 5–6 accommodate a added abundant alignment (eg, carpenter) and the aftermost two digits are the abstracted apprenticeship titles accessible aural anniversary discipline.
The belief (a) and (b) mentioned aloft may advance to two altered after-effects apropos anatomic accumulation membership. To abstain this, the afterward prioritisation was used: (1) attic layers, (2) architecture workers, (3) farmers, (4) healthcare workers and (5) appointment workers. All advice was complete to be accurate at 1 January anniversary year.
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OA was authentic based on the National Patient Register.[27] This annals contains abstracts on all bodies accepted to hospitals back 1977. The annals includes acquittal diagnoses of hospitalised patients advertence the capital medical acumen for analytic procedures or treatment. Acquittal diagnoses are coded by physicians, and back 1994, they accept been coded according to the 10th adaptation of the International Allocation of Diseases (ICD-10). Surgical procedures are registered by operation codes back 1996, coded according to the Danish adaptation of the Nordic Allocation of Surgical Procedures. A actuality was authentic to accept a hip OA if she (a) had a acquittal analysis of defined OA in several joints in hip, knee or bottom (ICD-10, M15–M17, M19) and (b) aural the aforementioned agenda year had a hip backup anaplasty performed (operation cipher KNFB) and a knee OA if she had (a) and (b) a knee backup (KNGB) aural the aforementioned year.
Age was computed as the age at 1 January anniversary year. Agenda year was categorised into three periods: 1981–1989, 1990–1999 and 2000–2006. Anniversary claimed assets acquired from the assets register[29] was for anniversary year categorised in quartiles based on the accomplished Danish population. Anniversary claimed unemployment accessible from the annals on Coherent Amusing Statistics was categorised in admeasurement of the year: ≤20%, 21%–80% and >80%. A actuality was advised to accept had a antecedent knee abrasion if the actuality back 1977 had been hospitalised with an adapted acquittal analysis (yes/no).
Each agent was articular for anniversary year from 1 January 1981 until 1 January 2006 and followed for aboriginal analysis of hip or knee OA from 1 January 1996 until 31 December 2006 or until afterlife or emigration, whichever came first. All analyses were performed alone for men and women and for anniversary acknowledgment group. Initially, age-standardised accident ante of OA were affected by absolute standardisation, application the age administration for both sexes accumulated (with 5-year age groups) of the appointment workers as the accepted population. HRs and 95% CIs for OA were estimated application Cox proportional hazards corruption models with age as the basal timescale. For a accustomed acknowledgment group, a actuality was included as apparent from the age at which she the aboriginal time was apparent in the group. A actuality was advised to be in the advertence accumulation if she at no time during the aftereffect was in any of the acknowledgment groups but in at atomic 1 year was in the ascendancy group—the age at access was age at aboriginal year as control. Age at avenue was age at event/censoring[31] —thus for example, a floor- and bricklayer was advised to be floor- and bricklayer from access to exit, alike admitting she during the aeon had had addition occupation. Cumulative years in the advised activity was summed dynamically abacus 1 year for anniversary year a actuality was in the accustomed activity and categorised as 1–5, 6–10 and >10 years. The Cox corruption models were adapted for year of access (three groups), anniversary claimed assets (four groups), anniversary claimed unemployment (three groups) and antecedent knee abrasion (yes/no). Anniversary of these variables was advised as actuality time-dependent. Analyses were performed application SAS (Proc TPHREG, SAS Institute Inc), V.9.1.
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