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The afterward are some of the biotech stocks that fabricated their way assimilate the Day's Gainers & Losers' account of October 17, 2017.
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GAINERS
1. Voyager Therapeutics Inc. (VYGR)
Gained 11.50% to abutting Tuesday's (Oct.17) trading at $22.89.
News: The Aggregation presented auspicious new abstracts accompanying to its atypical AAV gene assay capsids in a preclinical archetypal of Friedreich's ataxia.
The Company's atypical AAV gene assay capsids authenticate boundless gene alteration to the academician and analgesic bond of non-human primates afterwards a distinct intravenous administration. One ages afterwards dosing, abundant levels of frataxin-HA were bidding in the Central Nervous System.
Friedreich's anarchy is a severe, affiliated acoustic ache acquired by mutations in the frataxin gene arch to decreased announcement of frataxin (FXN), which after-effects in astringent acoustic impairment, accelerating accident of the adeptness to walk, ambiguous weakness, accident of sensation, as able-bodied as astringent and potentially baleful cardiomyopathy.
2. Rigel Pharmaceuticals Inc. (RIGL)
Gained 9.30% to abutting Tuesday's trading at $4.23.
News: No news
Recent event:
On October 10, 2017, the Aggregation appear the closing of its accessible alms of 20.81 actor shares of its accepted banal at a amount to the accessible of $3.35 each. The gross gain to Rigel from this alms were $69.73 million.
Near-term catalyst:
The Company's New Biologic Appliance for Tavalisse in alleviative patients with abiding or assiduous allowed thrombocytopenia is beneath FDA assay - with a accommodation date set for April 17, 2018.
3. XOMA Corp. (XOMA)
Gained 6.99% to abutting Tuesday's trading at $23.58.
News: No news
Pipeline:
The Company's advance candidates accommodate XOMA 358, beneath appearance II testing in patients with Hypoglycemia afterwards belly bypass surgery, and XOMA 213, which afresh accustomed absolute after-effects in a appearance II proof-of-concept abstraction in physiological hyperprolactinemia.
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Recent event:
-- On October 4, 2017, XOMA entered into new non-exclusive authorization agreements with three altered companies, Tizona Therapeutics, Inc., Torch Biosciences, Inc., and LakePharma for use of its proprietary phage affectation libraries for antibiotic discovery.XOMA's phage affectation libraries are accoutrement to accomplish animal recombinant antibodies with admirable specificity and aerial affinity.
Under these agreements, XOMA is acceptable to accept development and authoritative anniversary payments added single-digit royalties on net sales of products. Additionally, the acceding with LakePharma, a U.S.-based biologics casework company, enables it to advance its own antibodies appliance XOMA's library, as able-bodied as action the Company's library to its ample chump base. XOMA is acceptable to accept anniversary and ability payments for articles developed by LakePharma and as allotment of its applicant programs.
4. Foamix Pharmaceuticals Ltd. (FOMX)
Gained 6.36% to abutting Tuesday's trading at $6.69.
News: No news
Near-term catalysts:
-- Top-line after-effects from third appearance III Abscess analytic balloon for Minocycline Foam FMX101 accepted by mid-2018.-- Top-line after-effects from addled appearance of Appearance 3 affairs of contemporary Minocycline Foam 1.5%, FMX103 for the assay of moderate-to-severe abscess advancing by mid-2018.
5. Aptevo Therapeutics Inc. (APVO)
Gained 5.70% to abutting Tuesday's trading at $2.41.
News: The Company's pre-clinical biologic applicant APVO210 accustomed targeted Cytokine commitment for appliance in assorted autoimmune and anarchic diseases. The Aggregation looks advanced to advancing APVO210 appear analytic development.
Pipeline:
The Aggregation has two analytic biologic candidates - MOR209/ES414 monotherapy in patients with metastatic castration-resistant prostate cancer, beneath appearance I trial, and Otlertuzumab for abiding lymphocytic leukemia, beneath appearance II study.
The Aggregation additionally has 4 marketed drugs.
6. Agile Therapeutics Inc. (AGRX)
Gained 5.56% to abutting Tuesday's trading at $5.13.
News: The Aggregation presented added after-effects from its appearance III balloon of investigational low-dose accumulated hormonal contraceptive patch, Twirla, dubbed SECURE, at the 2017 North American Forum on Family Planning.
Near-term catalyst:
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-- Agile's New Biologic Appliance for Twirla is beneath FDA assay - with a accommodation date set for December 26, 2017. Twirla was angry bottomward by the FDA in 2013.
LOSERS
1. Allowed Design Corp. (IMDZ)
Lost 18.81% to abutting Tuesday's trading at $8.20.
News: The Aggregation affairs to admit a cardinal Appearance 3 balloon to abutment a Biologics Authorization Appliance for CMB305, a atypical blight vaccine, in patients with synovial bump in mid-2018.
The abstraction will accept 248 patients age-old twelve and older, and they will be randomized 1:1 to accept either CMB305 monotherapy or placebo. The balloon will accept progression chargeless adaptation (PFS) followed by all-embracing adaptation (OS) as co-primary endpoints. Depending on the amount of events, final PFS assay may action as aboriginal as 24 months from the aboriginal accommodating dosed.
2. Inotek Pharmaceuticals Corp. (ITEK)
Lost 14.29% to abutting Tuesday's trading at $2.22.
News: No news
Recent event:
On October 12, 2017, the Aggregation filed a basic proxy account for its ahead appear proposed alliance with Rocket Pharmaceuticals, a US-based gene assay company.
The alliance is accepted to abutting in the aboriginal division of 2018.
3. Ardelyx Inc. (ARDX)
Lost 14.06% to abutting Tuesday's trading at $5.50. This is the additional beeline day of accident for the stock.
Recent event:
-- On October 11, 2017, the Aggregation appear absolute after-effects from T3MPO-2, its additional Appearance 3 abstraction of Tenapanor for annoyed bowel affection with ache (IBS-C).The Aggregation expects to abide a New biologic Appliance for Tenapanor for annoyed bowel affection with ache in the additional bisected of 2018.
4. MannKind Corp. (MNKD)
Lost 12.36% to abutting Tuesday's trading at $4.75.
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News: No news
Recent event:
-- On October 11, 2017, the Aggregation appear a registered absolute alms of an accumulated of 10.16 actor shares of accepted banal at an alms amount of $6.00 per share, for gross gain of about $61 million. The alms was accepted to abutting on or about October 13, 2017.-- On October 2, 2017, the FDA accustomed an amend to the Afrezza label, apropos its accelerated access of action and continuance of effect.
5. Deciphera Pharmaceuticals Inc. (DCPH)
Lost 10.71% to abutting Tuesday's trading at $21.43.
News: No news
Recent event:
-- On October 3, 2017, the Aggregation bankrupt its antecedent accessible alms of 7.5 actor shares of its accepted banal at a accessible alms amount of $17.00 each.
Pipeline:
The Company's advance applicant is DCC-2618, currently in a first-in-human Appearance 1 analytic trial. DCC-2618 is in analytic development for the assay of KIT and/or PDGFRa-driven cancers, including gastrointestinal stromal tumors, glioblastoma multiforme and systemic mastocytosis.
6. Fulgent Genetics Inc. (FLGT)
Lost 9.31% to abutting Tuesday's trading at $3.80.
News: No news
Upcoming event:
The Aggregation is slated to address banking after-effects for its third division concluded September 30, 2017 in the aboriginal anniversary of November.
by RTT Staff Writer
For comments and feedback: editorial@rttnews.com
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