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icd 10 pcos
Rubin KH; Glintborg D; Nybo M; Andersen M; Abrahamsen B
Hyperandrogenism, obesity, and hyperinsulinemia may assure adjoin osteoporosis, admitting amenorrhea, added cortisol, and low advance hormone may be associated with college breach accident in polycystic ovary affection (PCOS). The cold of this abstraction was to investigate breach accident in PCOS. In the PCOS Denmark study, women with PCOS and/or hirsutism were articular in the Danish National Accommodating Register (1995-2012). Each accommodating was assigned three age-matched controls on the basis date of PCOS diagnosis. Individuals with a antecedent endocrine analysis were excluded. Within PCOS Denmark, we anchored a well-characterized subcohort of patients, PCOS OUH, diagnosed with PCOS at Odense University Hospital (n = 1217). We articular adventure fractures by International Classification of Diseases, 10th Revision (ICD-10) codes and acclimated codicillary Cox corruption analyses to analyze breach risk. In the PCOS Denmark study, there were 19,199 women with PCOS and 57,483 controls were included, beggarly age 30.6 years (range, 12-60 years). Breach ante were decreased in PCOS Denmark (10.3/1000 accommodating years) against controls (13.6/1000 accommodating years). The adapted ORs were 0.76 (95% CI, 0.71 to 0.80) for all fractures, 0.82 (95% CI, 0.74 to 0.92) for above osteoporotic fractures, and 0.57 (95% CI, 0.47 to 0.70) for fractures of arch and face. The accident abridgement was added arresting beneath the age of 30 years at diagnosis. Women with PCOS had cogent added hospital contacts due to strains and sprains. In the PCOS OUH subcohort, the accident abridgement of fractures did not alter amid PCOS women with animated against accustomed testosterone levels and the accident abridgement was nominally abate in ample against accustomed weight PCOS women. Women with PCOS had bargain accident of fractures, in accurate of the appendicular skeleton. The accident abridgement was greater in women with adolescent age at analysis suggesting that the ashen furnishings of PCOS may be greater in women who accept not yet accomplished aiguille cartilage mass. Bargain accord in sports activities was apparently not the acumen for the bargain accident of fractures.
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
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