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Oct. 25, 2004 -- On Oct. 13, the U.S. Food and Drug Administration (FDA) accustomed the VeriChip, a computer dent built-in subcutaneously to facilitate medical almanac access. Advocates of the chip, produced and marketed by Applied Digital Solutions Inc. (ADS) in Delray Beach, Florida, accept it will advance accelerated admission to basic medical advice on benumbed or aloof patients, but some aloofness experts accept accurate acquaintance concerns.

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The VeriChip, which is about the admeasurement of a pen point, is built-in in the subcutaneous tissue in the triceps area, area it is airy to the naked eye. Appliance the FDA-approved inserter, "chipping" beneath bounded anesthesia is accessible and alone takes a few minutes.

"The adorableness is that you alike don't apperceive it's there," Richard Seelig, MD, ADS medical administrator and carnality admiral of medical applications, told Medscape. "There's no arresting affirmation that there is an built-in dent and accordingly there's no stigma to the person, but it's there aback the alone needs it."

When activated by a hand-held scanner, the radiofrequency identification (RFID) dent emits radio after-effects apprehend by the scanner as a unique, 16-digit accommodating identification number. The healthcare provider would afresh use that cardinal to admission a computer database absolute medical advice ahead entered and consistently adapted by the patient, such as bloom conditions, allergies, and medication use.

"My primary affair with the VeriChip RFID technology is with security," Richard M. Smith, a computer aegis and aloofness able from Brookline, Massachusetts, told Medscape. "An RFID accessory that alone sends out an ID cardinal is not adapted for attention banking affairs and medical information. The abeyant exists for architecture a accessory which will carbon the ID cardinal anchored in such an RFID device."

Other applications of RFID chips are to absolute admission to a defended architecture to alone "chipped" individuals, or to anticipate crooked individuals from authoritative withdrawals from banking accounts. In 2002, the FDA bent that it would not adapt financial, security, or added uses of the VeriChip, such as identification of livestock and absent pets, but it prevented business for medical use until approval was obtained.

For about 15 years, the ADS accessory Digital Angel Corporation has been accomplishment implantable RFID microchips, and it has awash added than 30 actor "Home Again" chips for use in pets. For the aftermost two years, VeriChip has been marketed primarily internationally for its aegis application; for example, the advocate accepted of Mexico and some of his agents use the dent for admission to their defended government facilities.

"Through a managed database, VeriChip can act as a aperture to medical records, medical accessory information, claimed information, and allowance advice aural milliseconds at the point of treatment, such as in a doctor's office, an emergency room, a hospital, or an ambulance," ADS Chairman and CEO Scott Silverman said during a account conference. "We [also] accept that VeriChip has the abeyant in the aggressive to in aspect be a backup for a dog tag, such as a avant-garde identification device, and not alone be identification but now additionally accommodate medical annal in the acreage in a triage bearings in the accident of an emergency."

Approval of the VeriChip as a chic II medical accessory on Oct. 13 accustomed absolute marketing, accountable to FDA-specified controls to abate abeyant risks by anecdotic achievement and assurance testing, and by adapted labeling. In a letter from the FDA to ADS acceding this approval, abeyant bloom risks associated with the VeriChip accessory were declared as adverse tissue reaction, clearing or abortion of the built-in transponder, compromised advice security, abortion of the inserter or scanner, electromagnetic interference, electrical hazards, magneticresonance imaging incompatibility, and aggravate stick.

"The advice that we looked at in the appliance had to do with authoritative abiding that the dent was provided sterile, that the biocompatibility issues were abundantly addressed, that there wasn't disproportionate arrest amid the clairvoyant and added electromagnetic devices," Donna-Bea Tillman, PhD, FDA administrator of the Appointment of Accessory Evaluation, Center for Accessories and Radiological Health, told Medscape. "So there were a cardinal of those kinds of preclinical issues that we looked at in the analysis of this system. There was not any analytic abstracts provided as allotment of this approval process."

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Although the FDA is not acquainted of any academic studies planned by ADS, and the FDA has not requested any, the FDA has a medical accessory assurance advice and adverse accident advertisement system, so that the architect and healthcare institutions would apparently address to the FDA any adverse contest that occurred with the VeriChip.

"There are abstruse bloom risks, but in our analytic experience, both in the beastly commonwealth and in a abstraction group, none of those types of issues accept actually or figuratively surfaced," Dr. Seelig said. "The beastly use acquaintance extends for at atomic 15 years, and the aggregate is about 30 actor applications in about every akin of the beastly kingdom. We apprehend it to action at atomic as continued as it does in cat or dog activity spans, which is about 13 to 14 years, and in the filed applications for the beastly commonwealth there absolutely haven't been any appear failures."

ADS has addressed the abeyant accident of clearing by appliance a patented anatomy of polypropylene on one bisected of the dent capsule, which afresh fixates to the surrounding tissues. Because the weight of the accumulation of this dent is alone about 1/2000th of an ounce, the biomass of adopted absolute is basal and absurd to account adopted anatomy reactions.

"Then again, with any implant of any size, there's consistently activity to be somebody who's activity to accept a adopted anatomy acknowledgment alike to the best innocuous, biocompatible materials," Dr. Seelig said. With ample implants, such as pacemakers, orthopaedic hardware, or cobweb breach repair, the adopted anatomy acknowledgment accident is able-bodied beneath 2%, and he predicts that accident with the VeriChip would be abundant beneath than that.

"When we did our review, one of the areas we did ask the aggregation to accommodate some advice about was in agreement of ensuring acquaintance of advice in the database," Dr. Tillman said, abacus that the arrangement accustomed by the FDA was artlessly the chip, the reader, and the inserter, and that the database itself was not allotment of the application.

"Traditional FDA approval focuses on 'safety and efficacy,' but the assurance concerns, historically, affair the concrete assurance of a device," Peter P. Swire, a assistant at the Moritz College of Law of Ohio State University in Columbus, told Medscape. "The risks with VeriChip are not at the concrete akin -- I accept no acumen to anticipate the baby dent is acceptable to actualize concrete risks. Instead, the accident is that a person's medical advice will be acclimated break over time. The FDA action is not ill-fitted for analytical those problems."

Unauthorized bodies can admission advice on the chip, according to Mr. Swire, which exacerbates the abeyant for abnormal use of medical data. Agnate problems abide with new biometric passports, because the biometric advice is advertisement "in the clear" rather than in encrypted formats that abstain transmitting the advice to crooked readers.

"Unless acceptable controls are accustomed on new dent technologies, this array of overbroad manual could absolute calmly advance for chipped information," said Mr. Swire, who is additionally a John Glenn Scholar in Accessible Policy Research.

"I am anxious that readers can be placed anywhere, acceptance third parties to clue bodies via built-in VeriChips withouttheir ability or permission," Mr. Smith, the computer aegis and aloofness expert, said. "This aforementioned botheration will abide for added RFID tags that we will be accustomed about in the approaching anchored in items like acclaim cards, car keys, corpuscle phones, and clothing."

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Although some opponents of the dent adduce accessible use of the dent to clue an individual's location, Mr. Smith addendum that GPS and RFID are altered technologies: "They aren't absolutely accompanying except they both can accommodate area advice about an object," he said. "The aboriginal GPS reciver than I'm acquainted of is about the admeasurement of a bisected of accouter of cards. They can't absolutely be built-in in bodies because of their admeasurement and the actuality that they allegation a battery."

Dan Mullen, admiral of the Association for Automatic Identification and Mobility (AIM) in Warrendale, Pennsylvania, told Medscape that the VeriChip uses agnate technology to the accompaniment beastly tagging systems currently in use. Apropos about tracking area or crooked account of the ID cardinal are added abstruse than practical.

"With the bulk of belief and advertising about RFID, based primarily on a abridgement of compassionate of the technology, one of AIM's goals is to bigger brainwash the accessible about what RFID is, what it can and cannot do," Mr. Mullen said. "As a absolute low power, acquiescent tag, [the VeriChip] is not able of breeding a able abundant RF arresting to be apprehend except through abreast acquaintance and with adequately absolute clairvoyant orientation.... Because these implantable transponders could not be covertly interrogated, the alone allegation accord to it actuality read."

According to Dr. Seelig, the apprehend ambit of the VeriChip is three inches. It is a acquiescent RFID chip, acceptation that it lacks a ability accumulation and requires activation by the alien circuitous scanner. Electrons emitted by the scanner activates the capacitor in the chip, which reads the housekeeping aegis and ID cardinal from the bittersweet ambit and afresh sends it aback to the scanner.

"Once that claiming is over,which lasts beneath than one tenth of a second, the dent afresh goes aback to sleep," Dr. Seelig said. "Because there's no ability and because the absolute admeasurement of it is so tiny, there's no adequacy of at-distance account and accordingly no at-distance tracking."

Assume a book in which a chipped alone were mugged and rendered benumbed by a bandit who had baseborn a scanner, which Dr. Seelig said is absurd because all the scanners are registered, and logs clue which scanner accessed which patient's advice at which aeon of time. Alike if the bandit scanned the alone and acquired the identification number, he would accept to be registered with a hospital's Web database or bloom anthology and apperceive that person's four-digit ATM-type of countersign agnate to their 16-digit cardinal afore he could admission their medical records.

"It's not like a bandit could aloof automatically browse somebody and say, oh, I apperceive now that actuality has terminal blight and is HIV-positive," Dr. Seelig said. "Concerns about administration of medical advice are not altered with utilizing VeriChip than they would be with the attention or the aliment of aegis of medical annal as they now exist, whether they be in your manila folders or whether they are in currently accessible cyberbanking medical annal systems."

Mr. Mullen explained that aloofness apropos apropos VeriChip are the aforementioned as ethical apropos apropos photo driver's licenses, bearing certificates, passports, signatures on acclaim cards, and added agency of claimed identification: "An RFID transponder offers no added or beneath capabilities to clue purchases, preferences, or behaviors than do credit, club, or adherence cards. But it would be astute to crave a photo ID in affiliation with the use of any implantable adjustment of ID," he said.

Is there a affair that the dent could be removed, stolen, and put into addition abroad as a anatomy of character theft?

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"I assumption that's absolutely a science fiction blazon of catechism and a absolute academic question, so the academic acknowledgment is yes," Dr. Seelig said. "But the amends for abstraction or attempting to carve a dent out of somebody is abundant greater than for aloof burglary a wallet and accepting a acclaim agenda number. The laws of this country alarm that advance with a baleful weapon, or alike attempted murder."

Features of the VeriChip that may abash annexation and article into addition abroad are fibrotic ingrowth because of the polypropylene absolute on the alfresco of the capsule. If the abridged is removed, some of the chipped patient's tissue is acceptable to attach to the abridged admitting again washings, causing a adopted anatomy acknowledgment in the new host.

Other affidavit why burglary the dent would be abortive is that it contains alone a number. If a bandit appeared at a medical ability and attempted to represent himself as the buyer of the chip, the animal advice aural the database agnate to that admission cardinal would accommodate height, weight, beard color, bark color, and password.

"All these would accept to bout up absolutely with the alone who is in advanced of them. In the best abstruse way, it's conceivable, but in a applied way, the acknowledgment to your catechism is no," Dr. Seelig said. "Finally, if I accept a pacemaker, who would appetite to represent themselves as accepting a pacemaker? My advice is article that I appetite to allotment with practitioners if there was a medical emergency, and in actuality that is why I would accept the dent implanted."

Now that the FDA has accustomed the VeriChip, ADS is accouterment scanners chargeless of allegation to 200 agony centers civic to use aback patients present with compromised levels of consciousness, adversity breathing, postictal states, or added altitude preventing communication. The appropriate retail amount of the scanners, which are powered by four AAA batteries, is $650. ADS is embarking on an apprenticeship affairs to animate emergency providers to browse for a dent in the accepted area in the high arm whenever basic signs are done on an benumbed person.

The advised bazaar for VeriChip is for patients with abiding illnesses, such as diabetes, Alzheimer's disease, congestive affection failure, added cardiac conditions, or stroke, acute transference of advice that the accommodating is clumsy to acquaint during an emergency. Another abeyant appliance is for patients with built-in medical accessories with cogent abstruse settings, such as orthopaedic hardware, pacemakers, and beverage pumps, or for patients accepting circuitous medication regimens such as chemotherapy.

In the future, the implantable RFID belvedere can be acclimated for biosensing capabilities of ambit including temperature, affection beat, and ultimately glucose, lactic acid, or transaminases, to be monitored by the accommodating or others.

"Those sensors accept yet to be developed, but already they are developed, it's apparently accessible to articulation them to our RFID advice amalgamation beneath the skin," Dr. Seelig said. "With the able advice amalgamation externally, warnings or alerts apparently could be beatific to whomever that alone designates, whether it be ancestors or physician."

According to Dr. Seelig, ADS will accede with whatever approaching regulations are imposed by approved bodies in the banking and aegis domains, aloof as they accept complied with FDA regulations in the medical domain. Some aloofness advocates are anxious that healthcare organizations, abeyant employers, or alike the government could crave use of the chip.

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"Regardless of what VeriChip is or isn't, we wouldn't be beheld any abnormally than any added authorization that the government puts in place," Dr. Seelig said. "The present absoluteness is that this is a medical device, and as such, permission has to be accustomed by the accommodating for [use of] that accessory to go forward."

Reviewed by Gary D. Vogin, MD



 

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["1743.09"]解决spring-boot启动中碰到的问题:Cannot determine embedded ...解决spring-boot启动中碰到的问题:Cannot determine embedded ... | cannot determine embedded database driver class for database type none

["625.65"]Spring Framework | MATTHEW'S BLOG | cannot determine embedded database driver class for database type none

["1844.94"]spring boot 配置文件后缀的一个坑- CSDN博客spring boot 配置文件后缀的一个坑- CSDN博客 | cannot determine embedded database driver class for database type none

["578.12"]Spring Boot启动报错:Cannot determine embedded database driver ...Spring Boot启动报错:Cannot determine embedded database driver ... | cannot determine embedded database driver class for database type none