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icd 10 code for leukemia
Nedved AN; DeFrates SR; Hladnik LM; Stockerl-Goldstein KE
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OBJECTIVE: Appraise the furnishings of linezolid on hematologic outcomes in anew diagnosed patients with astute myeloid leukemia (AML) afterward consecration chemotherapy.
DESIGN: Single-center, retrospective, observational, accomplice study.
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SETTING: Large, tertiary affliction bookish medical center.
PATIENTS: A absolute of 225 patients ≥ 18 years accepted amid December 2010 and 2013 with anew diagnosed AML were adjourned for inclusion. Patients were articular through the use of ICD-9 codes and chemotherapy ordered via the computerized physician adjustment access system. Sixty-eight patients met admittance belief and were aggregate into two accoutrements based on antimicrobial treatment: LZD accumulation (linezolid additional gram-negative antimicrobial, n=21) or ascendancy accumulation (vancomycin or daptomycin additional gram-negative antimicrobial, n=47).
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INTERVENTIONS: The LZD accumulation accustomed linezolid ≥ 72 hours. The ascendancy accumulation accustomed vancomycin or daptomycin ≥ 72 hours. If patients switched continued gram-positive therapy, they were included in the LZD accumulation as continued as they had accustomed ≥ 72 hours of linezolid.
MEASUREMENTS/RESULTS: The primary end point of time to neutrophil accretion was not statistically altered (28 canicule for LZD accumulation vs 26 canicule for ascendancy group; p=0.675). The agreed subgroup assay of patients who accustomed ≥ 14 canicule of linezolid approved statistically agnate average times to neutrophil accretion (29 canicule for LZD accumulation vs 26 canicule for ascendancy group; p=0.487). Absolute continuance of continued gram-positive antimicrobial assay was decidedly best in the LZD accumulation (27 canicule vs 16 days; p<0.001). Secondary end credibility not begin to be statistically cogent included platelet calculation at time of neutrophil recovery, continuance of neutropenia, and breadth of hospital stay.
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CONCLUSIONS: There were no cogent differences in hematologic outcomes in anew diagnosed AML patients who accustomed linezolid for continued gram-positive antimicrobial advantage afterward consecration chemotherapy. This abstraction provides new acumen with a primary focus on the furnishings of hematologic outcomes back application linezolid in a categorical astute leukemia population. Further abstraction is acceptable with beyond populations to appraise the abeyant adverse furnishings linezolid may accept in patients with astute leukemia.
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
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